Triggering of Programmed Erythrocyte Death by Alantolactone

Triggering of Programmed Erythrocyte Death by Alantolactone

The sesquiterpene alantolactone counteracts malignancy, an effect at least in part due to stimulation of suicidal death or apoptosis of tumor cells. Signaling of alantolactone induced apoptosis involves altered gene expression and mitochondrial depolarization. Erythrocytes lack mitochondria and nucl...

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Bibliographic Details
Main Authors: Kousi Alzoubi, Salvatrice Calabrò, Jasmin Egler, Caterina Faggio, Florian Lang
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Toxins
Subjects:
phosphatidylserine
alantolactone
ceramide
oxidative stress
cell volume
eryptosis
Online Access:http://www.mdpi.com/2072-6651/6/12/3596

Internet

http://www.mdpi.com/2072-6651/6/12/3596

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