Delivery of Exogenous Antigens to Induce Cytotoxic CD8+ T Lymphocyte Responses

Vaccines intended to induce a cytotoxic CD8+ T-cell response are highly sought after. However, some of these vaccines can be problematic if they replicate in the host. An alternative strategy is to exploit cross-presentation of exogenous antigens to express peptides on major histocompatibility compl...

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Bibliographic Details
Main Authors: Julia Kim, Vandana Gambhir, Attiya Alatery, Sameh Basta
Format: Article
Language:English
Published: Hindawi Limited 2010-01-01
Series:Journal of Biomedicine and Biotechnology
Online Access:http://dx.doi.org/10.1155/2010/218752