Distribution, Evolution, Catalytic Mechanism, and Physiological Functions of the Flavin-Based Electron-Bifurcating NADH-Dependent Reduced Ferredoxin: NADP+ Oxidoreductase

Distribution, Evolution, Catalytic Mechanism, and Physiological Functions of the Flavin-Based Electron-Bifurcating NADH-Dependent Reduced Ferredoxin: NADP+ Oxidoreductase

NADH-dependent reduced ferredoxin:NADP+ oxidoreductase (Nfn) is an electron-bifurcating enzyme first discovered in the strict anaerobes Clostridium kluyveri and Moorella thermoacetica. In vivo, Nfn catalyzes the endergonic reduction of NADP+ with NADH coupled to the exergonic reduction of NADP+ with...

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Bibliographic Details
Main Authors: Jiyu Liang, Haiyan Huang, Shuning Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
flavin-based electron bifurcation
Nfn
gene fusion/fission
lateral gene transfer
structure
physiological function
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00373/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00373/full

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