Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition

Ischemia preconditioning is neuroprotective in a rat cerebral ischemic injury model through autophagy activation and apoptosis inhibition

Sublethal ischemic preconditioning (IPC) is a powerful inducer of ischemic brain tolerance. However, its underlying mechanisms are still not well understood. In this study, we chose four different IPC paradigms, namely 5 min (5 min duration), 5×5 min (5 min duration, 2 episodes, 15-mi...

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Bibliographic Details
Main Authors: D.Y. Xia, W. Li, H.R. Qian, S. Yao, J.G. Liu, X.K. Qi
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2013-08-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Ischemic preconditioning
Autophagy
Apoptosis
Focal cerebral ischemic reperfusion
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700580&lng=en&tlng=en

Internet

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2013000700580&lng=en&tlng=en

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