Accurate Detection of the Four Most Prevalent Carbapenemases in E. coli and K. pneumoniae by High-Resolution Mass Spectrometry

Accurate Detection of the Four Most Prevalent Carbapenemases in E. coli and K. pneumoniae by High-Resolution Mass Spectrometry

BackgroundAt present, phenotypic growth inhibition techniques are used in routine diagnostic microbiology to determine antimicrobial resistance of bacteria. Molecular techniques such as PCR are often used for confirmation but are indirect as they detect particular resistance genes. A direct techniqu...

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Bibliographic Details
Main Authors: Dimard E. Foudraine, Lennard J. M. Dekker, Nikolaos Strepis, Michiel L. Bexkens, Corné H. W. Klaassen, Theo M. Luider, Wil H. F. Goessens
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-11-01
Series:Frontiers in Microbiology
Subjects:
carbapenemases
Eschericha coli
Klebsiella pneumoniae
mass spectrometry – LC-MS/MS
parallel reaction monitoring
antimicrobial resistance
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02760/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.02760/full

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