Common FLG mutation K4671X not associated with atopic dermatitis in Han Chinese in a family association study.

Common FLG mutation K4671X not associated with atopic dermatitis in Han Chinese in a family association study.

BACKGROUND: Filaggrin gene (FLG) mutations have been identified as the cause of ichthyosis vulgaris (IV) and major predisposing factors for atopic dermatitis (AD). The relationship among AD, IV and FLG mutations has not been clarified yet. Mutations 3321delA and K4671X, two of the most common mutati...

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Bibliographic Details
Main Authors: Ruhong Cheng, Ming Li, Hui Zhang, Yifeng Guo, Xilan Chen, Jianfeng Tao, Aifang Jiang, Jiecheng Gan, Huaishan Qi, Hong Yu, Wanqing Liao, Zhirong Yao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3496733?pdf=render

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http://europepmc.org/articles/PMC3496733?pdf=render

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