Downregulation of CXCR4 in Metastasized Breast Cancer Cells and Implication in Their Dormancy.

Our understanding of the mechanism of cancer dormancy is emerging, but the underlying mechanisms are not fully understood. Here we analyzed mouse xenograft tumors derived from human breast cancer tissue and the human breast cancer cell line MDA-MB-231 to identify the molecules associated with cancer...

Full description

Bibliographic Details
Main Authors: Kentaro Nobutani, Yohei Shimono, Kiyohito Mizutani, Yuki Ueda, Toshihiro Suzuki, Midori Kitayama, Akihiro Minami, Kenji Momose, Kohta Miyawaki, Koichi Akashi, Takeshi Azuma, Yoshimi Takai
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4470829?pdf=render