Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber’s Hereditary Optic Neuropathy Cells

Evidence for Detrimental Cross Interactions between Reactive Oxygen and Nitrogen Species in Leber’s Hereditary Optic Neuropathy Cells

Here we have collected evidence suggesting that chronic changes in the NO homeostasis and the rise of reactive oxygen species bioavailability can contribute to cell dysfunction in Leber’s hereditary optic neuropathy (LHON) patients. We report that peripheral blood mononuclear cells (PBMCs), derived...

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Bibliographic Details
Main Authors: Micol Falabella, Elena Forte, Maria Chiara Magnifico, Paolo Santini, Marzia Arese, Alessandro Giuffrè, Kristina Radić, Luciana Chessa, Giulia Coarelli, Maria Chiara Buscarinu, Rosella Mechelli, Marco Salvetti, Paolo Sarti
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/3187560

Internet

http://dx.doi.org/10.1155/2016/3187560

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