Dynamic control of modeled tonic-clonic seizure states with closed-loop stimulation

Seizure control using deep brain stimulation (DBS) provides an alternative therapy to patients with intractable and drug resistant epilepsy. This paper presents novel DBS stimulus protocols to disrupt seizures. Two protocols are presented: open-loop stimulation and a closed-loop feedback system util...

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Bibliographic Details
Main Authors: Bryce eBeverlin II, Theoden I Netoff
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2012.00126/full