Pediatric Dosing and Body Size in Biotherapeutics
Although pediatric doses for biotherapeutics are often based on patients' body weight (mg/kg) or body surface area (mg/m2), linear body size dose adjustment is highly empirical. Growth and maturity are also important factors that affect the absorption, distribution, metabolism and excretion (AD...
Main Authors: | Hartmut Derendorf, Rong Shi |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2010-12-01
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Series: | Pharmaceutics |
Subjects: | |
Online Access: | http://www.mdpi.com/1999-4923/2/4/389/ |
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