Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help

Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help

Incorporation of immunodominant T-helper epitopes of licensed vaccines into virus-like particles (VLP) allows to harness T-helper cells induced by the licensed vaccines to provide intrastructural help (ISH) for B-cell responses against the surface proteins of the VLPs. To explore whether ISH could a...

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Bibliographic Details
Main Authors: Dominik Damm, Leonardo Rojas-Sánchez, Hannah Theobald, Viktoriya Sokolova, Richard T. Wyatt, Klaus Überla, Matthias Epple, Vladimir Temchura
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Nanomaterials
Subjects:
nano-vaccines
hiv-1 env trimers
b-cell targeting
intrastructural help
Online Access:https://www.mdpi.com/2079-4991/9/10/1389

Internet

https://www.mdpi.com/2079-4991/9/10/1389

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