Screening for Stress Resistance Mutations in the Mouse

Screening for Stress Resistance Mutations in the Mouse

Longevity is correlated with stress resistance in many animal models. However, previous efforts through the boosting of the antioxidant defense system did not extend life span, suggesting that longevity related stress resistance is mediated by other uncharacterized pathways. We have developed a hi...

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Bibliographic Details
Main Authors: Wallace S Chick, Michael eLudwig, Xiaoyun eZhao, David eKitzenberg, Kristina eWilliams, Thomas E Johnson
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Genetics
Subjects:
Embryonic Stem Cells
Mice
Paraquat
Forward genetics
Stress resistance
piggyBac transposon
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00310/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00310/full

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