Age-dependent changes in intrinsic neuronal excitability in subiculum after status epilepticus.

Kainic acid-induced status epilepticus (KA-SE) in mature rats results in the development of spontaneous recurrent seizures and a pattern of cell death resembling hippocampal sclerosis in patients with temporal lobe epilepsy. In contrast, KA-SE in young animals before postnatal day (P) 18 is less lik...

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Bibliographic Details
Main Authors: Sungkwon Chung, Nelson Spruston, Sookyong Koh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4361192?pdf=render