STAT3 governs the HIF-1α response in IL-15 primed human NK cells

Abstract Natural killer (NK) cells mediate innate host defense against microbial infection and cancer. Hypoxia and low glucose are characteristic for these tissue lesions but do not affect early interferon (IFN) γ and CC chemokine release by interleukin 15 (IL-15) primed human NK cells in vitro. Hyp...

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Bibliographic Details
Main Authors: Anna Coulibaly, Sonia Y. Velásquez, Nina Kassner, Jutta Schulte, Maria Vittoria Barbarossa, Holger A. Lindner
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-84916-0