Endoplasmic Reticulum (ER) Stress and Endocrine Disorders

Endoplasmic Reticulum (ER) Stress and Endocrine Disorders

The endoplasmic reticulum (ER) is the organelle where secretory and membrane proteins are synthesized and folded. Unfolded proteins that are retained within the ER can cause ER stress. Eukaryotic cells have a defense system called the “unfolded protein response” (UPR), which protects cells from ER s...

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Bibliographic Details
Main Authors: Daisuke Ariyasu, Hiderou Yoshida, Yukihiro Hasegawa
Format: Article
Language:English
Published: MDPI AG 2017-02-01
Series:International Journal of Molecular Sciences
Subjects:
endoplasmic reticulum stress
endocrine disorder
PKR-like endoplasmic reticulum kinase (PERK)
activating transcription factor 6 (ATF6)
inositol requirement 1 (IRE1)
old astrocyte specifically induced substance (OASIS) family
chemical chaperone
Online Access:http://www.mdpi.com/1422-0067/18/2/382

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http://www.mdpi.com/1422-0067/18/2/382

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