Determination of Muscone in Rats Plasma following Oral Administration of Artificial Musk: Using of Combined Headspace Gas Chromatography-Mass Spectrometry

To develop an analytical method for determination of plasma concentrations of muscone in rats following oral administration of artificial musk, with the aim of investigating the pharmacokinetic profile of artificial musk. Plasma samples were pretreated with acetonitrile to precipitate proteins. Head...

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Bibliographic Details
Main Authors: Qibiao Wu, Haitao Li, Yujing Leng, Haishan Deng, Haibo Cheng, Weixing Shen
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:Journal of Spectroscopy
Online Access:http://dx.doi.org/10.1155/2014/906928