Organoid in colorectal cancer: progress and challenges

Abstract. Patient-derived tumor organoids (PDOs) currently represent important modeling tools in pre-clinical investigation of malignancies. Organoid cultures conserve the genetic and phenotypic characteristics of the original tumor and maintain its heterogeneity, allowing their application in many...

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Bibliographic Details
Main Authors: Deng-Bo Ji, Ai-Wen Wu, Qiang Shi
Format: Article
Language:English
Published: Wolters Kluwer 2020-08-01
Series:Chinese Medical Journal
Online Access:http://journals.lww.com/10.1097/CM9.0000000000000882