GSTpi regulates VE-cadherin stabilization through promoting S-glutathionylation of Src

GSTpi is a Phase II metabolic enzyme which is originally considered as an important facilitator of cellular detoxification. Here, we found that GSTpi stabilized VE-cadherin in endothelial cell membrane through inhibiting VE-cadherin phosphorylation and VE-cadherin/catenin complex dissociation, and c...

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Bibliographic Details
Main Authors: Yang Yang, Xiaoliang Dong, Shuangning Zheng, Jinbing Sun, Juan Ye, Jiao Chen, Yuan Fang, Bing Zhao, Zhimin Yin, Peng Cao, Lan Luo
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719312133