Periodic heat shock accelerated the chondrogenic differentiation of human mesenchymal stem cells in pellet culture.

Osteoarthritis (OA) is one of diseases that seriously affect elderly people's quality of life. Human mesenchymal stem cells (hMSCs) offer a potential promise for the joint repair in OA patients. However, chondrogenic differentiation from hMSCs in vitro takes a long time (∼ 6 weeks) and differen...

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Bibliographic Details
Main Authors: Jing Chen, Chenghai Li, Sihong Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3954764?pdf=render