Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody

Structural Basis for Neutralization and Protection by a Zika Virus-Specific Human Antibody

Summary: We previously reported a human monoclonal antibody, ZK2B10, capable of protection against Zika virus (ZIKV) infection and microcephaly in developing mouse embryos. Here, we report the structural features and mechanism of action of ZK2B10. The crystal structure at a resolution of 2.32 Å reve...

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Bibliographic Details
Main Authors: Lin Wang, Ruoke Wang, Lei Wang, Haijing Ben, Lei Yu, Fei Gao, Xuanling Shi, Chibiao Yin, Fuchun Zhang, Ye Xiang, Linqi Zhang
Format: Article
Language:English
Published: Elsevier 2019-03-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719302414

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http://www.sciencedirect.com/science/article/pii/S2211124719302414

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