Selective decrease of components of the creatine kinase system and ATP synthase complex in chronic Chagas disease cardiomyopathy.

BACKGROUND: Chronic Chagas disease cardiomyopathy (CCC) is an inflammatory dilated cardiomyopathy with a worse prognosis than other cardiomyopathies. CCC occurs in 30 % of individuals infected with Trypanosoma cruzi, endemic in Latin America. Heart failure is associated with impaired energy metaboli...

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Main Authors: Priscila Camillo Teixeira, Ronaldo Honorato Barros Santos, Alfredo Inácio Fiorelli, Angelina Morand Bianchi Bilate, Luiz Alberto Benvenuti, Noedir Antonio Stolf, Jorge Kalil, Edecio Cunha-Neto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-06-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC3125151?pdf=render