Rationally designed Spot 42 RNAs with an inhibition/toxicity profile advantageous for engineering E. coli
Abstract Bacterial regulatory small RNAs (sRNAs) have shown promise for gene knock‐down studies and metabolic engineering. However, some mRNAs might be difficult to target due to poor binding by the Hfq chaperone, individual synthetic sRNAs can have off‐target effects, potential sRNA toxicities have...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-03-01
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| Series: | Engineering Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/eng2.12126 |