FHF-independent conduction of action potentials along the leak-resistant cerebellar granule cell axon

FHF-independent conduction of action potentials along the leak-resistant cerebellar granule cell axon

FHFs are known to regulate voltage-gated sodium channels (NaVs). Here, the authors compare the role of FHFs in cerebellar granule cell propagation, and find NaVs in the distal axon function independently of FHFs, allowing for faster inactivation rates and reducing energy demands during repetitive sp...

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Bibliographic Details
Main Authors: Katarzyna Dover, Christopher Marra, Sergio Solinas, Marko Popovic, Sathyaa Subramaniyam, Dejan Zecevic, Egidio D’Angelo, Mitchell Goldfarb
Format: Article
Language:English
Published: Nature Publishing Group 2016-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms12895

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https://doi.org/10.1038/ncomms12895

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