Anti-Inflammatory Mechanisms of Koreanaside A, a Lignan Isolated from the Flower of <i>Forsythia koreana</i>, against LPS-Induced Macrophage Activation and DSS-Induced Colitis Mice: The Crucial Role of AP-1, NF-κB, and JAK/STAT Signaling

The current treatment options for inflammatory bowel disease (IBD) are unsatisfactory. Therefore, novel and safer therapies are needed. We previously reported that koreanaside A (KA) showed high radical scavenging activity and suppressed vascular cell adhesion molecule 1 (VCAM-1) expression in vascu...

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Bibliographic Details
Main Authors: Tae-Woo Kim, Ji-Sun Shin, Kyung-Sook Chung, Yeong-Geun Lee, Nam-In Baek, Kyung-Tae Lee
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Cells
Subjects:
ka
Online Access:https://www.mdpi.com/2073-4409/8/10/1163