Burkholderia pseudomallei Differentially Regulates Host Innate Immune Response Genes for Intracellular Survival in Lung Epithelial Cells.

BACKGROUND:Burkholderia pseudomallei, the causative agent of melioidosis poses a serious threat to humankind. B. pseudomallei secretes numerous virulence proteins that alter host cell functions to escape from intracellular immune sensors. However, the events underlying disease pathogenesis are poorl...

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Bibliographic Details
Main Authors: Kumutha Malar Vellasamy, Vanitha Mariappan, Esaki M Shankar, Jamuna Vadivelu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:http://europepmc.org/articles/PMC4930195?pdf=render