Differential Effects of the Toll-like Receptor 2 Agonists, PGN and PAM3CSK4, on Substance P-Induced Human Mast Cell Activation
Mast cells play important roles in innate immunity through their activation via toll-like receptors (TLRs) but also contribute to neuroimmunological responses and inflammation through their activation by the neuropeptide substance P (SP) via Gα i/o proteins. This study aims to compare the effects of...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SAGE Publishing
2013-09-01
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| Series: | European Journal of Inflammation |
| Online Access: | https://doi.org/10.1177/1721727X1301100314 |