A phosphorylation defective retinoic acid receptor mutant mimics the effects of retinoic acid on EGFR mediated AP-1 expression and cancer cell proliferation
<p>Abstract</p> <p>Background</p> <p>The effects of the vitamin A metabolite retinoic acid (RA) are mediated at the transcriptional level by retinoic acid receptors (RAR). These proteins are part of a superfamily of transcription factors which activate target gene expre...
Main Authors: | Kim Randie, Crowe David L |
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Format: | Article |
Language: | English |
Published: |
BMC
2002-10-01
|
Series: | Cancer Cell International |
Online Access: | http://www.cancerci.com/content/2/1/15 |
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