A phosphorylation defective retinoic acid receptor mutant mimics the effects of retinoic acid on EGFR mediated AP-1 expression and cancer cell proliferation

<p>Abstract</p> <p>Background</p> <p>The effects of the vitamin A metabolite retinoic acid (RA) are mediated at the transcriptional level by retinoic acid receptors (RAR). These proteins are part of a superfamily of transcription factors which activate target gene expre...

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Bibliographic Details
Main Authors: Kim Randie, Crowe David L
Format: Article
Language:English
Published: BMC 2002-10-01
Series:Cancer Cell International
Online Access:http://www.cancerci.com/content/2/1/15