Optical Redox Imaging of Treatment Responses to Nampt Inhibition and Combination Therapy in Triple-Negative Breast Cancer Cells

Optical Redox Imaging of Treatment Responses to Nampt Inhibition and Combination Therapy in Triple-Negative Breast Cancer Cells

We evaluated the utility of optical redox imaging (ORI) to identify the therapeutic response of triple-negative breast cancers (TNBC) under various drug treatments. Cultured HCC1806 and MDA-MB-231 cells treated with FK866 (nicotinamide phosphoribosyltransferase (Nampt) inhibitor), FX11 (lactate dehy...

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Bibliographic Details
Main Authors: Allison Podsednik, Jinxia Jiang, Annemarie Jacob, Lin Z. Li, He N. Xu
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:International Journal of Molecular Sciences
Subjects:
NADH and flavoproteins containing FAD
redox ratio
FK866/APO866
paclitaxel/Taxol
nicotinamide riboside
FX11
Online Access:https://www.mdpi.com/1422-0067/22/11/5563

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https://www.mdpi.com/1422-0067/22/11/5563

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