Anti-angiogenic effects of a mutant endostatin: a new prospect for treating retinal and choroidal neovascularization.

Pathological fundus angiogenesis is a major cause of vision loss in retina diseases. Endostatin, a C-terminal fragment of collagen XVIII, is an endogenous anti-angiogenic protein. The present study aimed to investigate the in vitro and in vivo anti-angiogenic properties of two proteins: an N-termina...

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Bibliographic Details
Main Authors: Yujing Bai, Min Zhao, Chunfang Zhang, Shanshan Li, Yun Qi, Bin Wang, Lvzhen Huang, Xiaoxin Li
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4224489?pdf=render