A Metabolomic Approach to Target Compounds from the Asteraceae Family for Dual COX and LOX Inhibition

The application of metabolomics in phytochemical analysis is an innovative strategy for targeting active compounds from a complex plant extract. Species of the Asteraceae family are well-known to exhibit potent anti-inflammatory (AI) activity. Dual inhibition of the enzymes COX-1 and 5-LOX is essent...

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Bibliographic Details
Main Authors: Daniela A. Chagas-Paula, Tong Zhang, Fernando B. Da Costa, RuAngelie Edrada-Ebel
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Metabolites
Subjects:
COX
LOX
Online Access:http://www.mdpi.com/2218-1989/5/3/404