PLAGL2 and POFUT1 are regulated by an evolutionarily conserved bidirectional promoter and are collaboratively involved in colorectal cancer by maintaining stemnessResearch in Context

Background: Our previous study revealed that PLAGL2 or POFUT1 can promote tumorigenesis and maintain significant positive correlations in colorectal cancer (CRC). However, the mechanism leading to the co-expression and the underlying functional and biological implications remain unclear. Methods: Cl...

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Bibliographic Details
Main Authors: Daojiang Li, Changwei Lin, Nanpeng Li, Yuheng Du, Chunxing Yang, Yang Bai, Zhicai Feng, Chen Su, Runliu Wu, Shenglei Song, Peicheng Yan, Miao Chen, Arad Jain, Lihua Huang, Yi Zhang, Xiaorong Li
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:EBioMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396419304323