Neurogenesis Potential Evaluation and Transcriptome Analysis of Fetal Hypothalamic Neural Stem/Progenitor Cells With Prenatal High Estradiol Exposure

Neurogenesis Potential Evaluation and Transcriptome Analysis of Fetal Hypothalamic Neural Stem/Progenitor Cells With Prenatal High Estradiol Exposure

High maternal estradiol is reported to induce metabolic disorders by modulating hypothalamic gene expression in offspring. Since neurogenesis plays a crucial role during hypothalamus development, we explored whether prenatal high estradiol exposure (HE) affects proliferation and differentiation of f...

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Bibliographic Details
Main Authors: Huihui Wang, Chengliang Zhou, Min Hou, Hefeng Huang, Yun Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Genetics
Subjects:
prenatal exposure
estradiol
neural stem/progenitor cells
neurogenesis
RNA sequencing
gene set enrichment analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2021.677935/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2021.677935/full

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