Population genomics of the immune evasion (var) genes of Plasmodium falciparum.

Population genomics of the immune evasion (var) genes of Plasmodium falciparum.

Var genes encode the major surface antigen (PfEMP1) of the blood stages of the human malaria parasite Plasmodium falciparum. Differential expression of up to 60 diverse var genes in each parasite genome underlies immune evasion. We compared the diversity of the DBLalpha domain of var genes sampled f...

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Bibliographic Details
Main Authors: Alyssa E Barry, Aleksandra Leliwa-Sytek, Livingston Tavul, Heather Imrie, Florence Migot-Nabias, Stuart M Brown, Gilean A V McVean, Karen P Day
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1828697?pdf=render

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http://europepmc.org/articles/PMC1828697?pdf=render

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