Inflammatory monocytes are detrimental to the host immune response during acute infection with Cryptococcus neoformans.

Cryptococcus neoformans is a leading cause of invasive fungal infections among immunocompromised patients. However, the cellular constituents of the innate immune response that promote clearance versus progression of infection upon respiratory acquisition of C. neoformans remain poorly defined. In t...

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Bibliographic Details
Main Authors: Lena J Heung, Tobias M Hohl
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-03-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1007627