MDM2 antagonists as a novel treatment option for acute myeloid leukemia: perspectives on the therapeutic potential of idasanutlin (RG7388)

Arushi Khurana, Danielle A Shafer Department of Internal Medicine, Division of Hematology, Oncology & Palliative Care, Virginia Commonwealth University, Richmond, VA 23298, USA Abstract: Acute myeloid leukemia (AML) is a clonal heterogenous malignancy of the myeloid cells with a poor progn...

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Bibliographic Details
Main Authors: Khurana A, Shafer DA
Format: Article
Language:English
Published: Dove Medical Press 2019-04-01
Series:OncoTargets and Therapy
Subjects:
AML
Online Access:https://www.dovepress.com/mdm2-antagonists-as-a-novel-treatment-option-for-acute-myeloid-leukemi-peer-reviewed-article-OTT