Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix.

Age-related collagen turnover of the interstitial matrix and basement membrane: Implications of age- and sex-dependent remodeling of the extracellular matrix.

The extracellular matrix (ECM) plays a vital role in maintaining normal tissue function. Collagens are major components of the ECM and there is a tight equilibrium between degradation and formation of these proteins ensuring tissue health and homeostasis. As a consequence of tissue turnover, small c...

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Bibliographic Details
Main Authors: Stephanie N Kehlet, Nicholas Willumsen, Gabriele Armbrecht, Roswitha Dietzel, Susanne Brix, Kim Henriksen, Morten A Karsdal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5875766?pdf=render

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http://europepmc.org/articles/PMC5875766?pdf=render

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