Pneumococcal serotype determines growth and capsule size in human cerebrospinal fluid

Abstract Background The polysaccharide capsule is a major virulence factor of S. pneumoniae in diseases such as meningitis. While some capsular serotypes are more often found in invasive disease, high case fatality rates are associated with those serotypes more commonly found in asymptomatic coloniz...

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Bibliographic Details
Main Authors: Annelies Müller, Anke Salmen, Suzanne Aebi, Linda de Gouveia, Anne von Gottberg, Lucy J. Hathaway
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Microbiology
Subjects:
Online Access:https://doi.org/10.1186/s12866-020-1700-7