Hydrogen Sulfide Attenuated Sepsis-Induced Myocardial Dysfunction Through TLR4 Pathway and Endoplasmic Reticulum Stress

Hydrogen Sulfide Attenuated Sepsis-Induced Myocardial Dysfunction Through TLR4 Pathway and Endoplasmic Reticulum Stress

Aims: We examined the change in endogenous hydrogen sulfide (H2S) production and its role in sepsis-induced myocardial dysfunction (SIMD).Results: Significant elevations in plasma cardiac troponin I (cTnI), creatine kinase (CK), tumor necrosis factor-α (TNF-α), and interleukin-1β (IL-1β) were noted...

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Bibliographic Details
Main Authors: Yu-hong Chen, Xu Teng, Zhen-jie Hu, Dan-yang Tian, Sheng Jin, Yu-ming Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Physiology
Subjects:
sepsis
myocardial dysfunction
hydrogen sulfide
Toll-like receptor 4
endoplasmic reticulum stress
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2021.653601/full

Internet

https://www.frontiersin.org/articles/10.3389/fphys.2021.653601/full

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