Developmental Competence and Pluripotency Gene Expression of Cattle Cloned Embryos Derived from Donor Cells Treated with 5-aza-2'-deoxycytidine

Developmental Competence and Pluripotency Gene Expression of Cattle Cloned Embryos Derived from Donor Cells Treated with 5-aza-2'-deoxycytidine

Background Reconstructed embryos from terminally differentiated somatic cells have revealed high levels of genomic methylation which results in inappropriate expression patterns of imprinted and non-imprinted genes. These aberrant expressions are probably responsible for different abnormalities duri...

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Bibliographic Details
Main Authors: Farnoosh Jafarpour, Sayed Morteza Hosseini, Mahdi Hajian, Mohsen Forouzanfar, Parvaneh Abedi, Laleh Hosseini, Somaye Ostadhosseini, Soghra Gholami, Mohammad Hossein Nasr Esfahani
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2011-01-01
Series:International Journal of Fertility and Sterility
Subjects:
epigenesis
nuclear reprogramming
nuclear transfer
Online Access:http://www.ijfs.ir/article_45069_0fbede76ae076f8b851bc96d3cbede2b.pdf

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http://www.ijfs.ir/article_45069_0fbede76ae076f8b851bc96d3cbede2b.pdf

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