Uses of Anthranilic Acid for the Synthesis of Dihydroquinazolin Derivatives with Antitumor, Anti-proliferative and Pim-1kinase Activities
The reaction of anthranilic acid with ethoxycarbonylisothiocyanate gave the ethyl 4-oxo-2-thioxo-1,2-dihydroquinazoline-3(4H)-carboxylate (4). The reaction of compound 4 with hydrazine hydrate and a-halocarbonyl derivatives was found to give either hydrazono or S-alkylated products. Heterocyclizatio...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Slovenian Chemical Society
2018-09-01
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| Series: | Acta Chimica Slovenica |
| Subjects: | |
| Online Access: | https://journals.matheo.si/index.php/ACSi/article/view/4146 |