Coagulation factor 9-deficient mice are protected against dextran sulfate sodium-induced colitis

Coagulation factor 9-deficient mice are protected against dextran sulfate sodium-induced colitis

Patients with inflammatory bowel disease (IBD) are susceptible to thromboembolism. Interestingly, IBD occurs less frequently in patients with inherited bleeding disorders. Therefore, we analyzed whether F9-deficiency is protective against the onset of acute colitis in a genetic hemophilia B mouse mo...

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Bibliographic Details
Main Authors: Avinash Khandagale, Jens M. Kittner, Amrit Mann, Stefanie Ascher, Bettina Kollar, Christoph Reinhardt
Format: Article
Language:English
Published: The Company of Biologists 2018-07-01
Series:Biology Open
Subjects:
Hemophilia B
Coagulation factor IX
Toll-like receptor-2
Colitis
Microbiota
Online Access:http://bio.biologists.org/content/7/7/bio034140

Internet

http://bio.biologists.org/content/7/7/bio034140

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