The Third Intron of the Interferon Regulatory Factor-8 Is an Initiator of Repressed Chromatin Restricting Its Expression in Non-Immune Cells.

The Third Intron of the Interferon Regulatory Factor-8 Is an Initiator of Repressed Chromatin Restricting Its Expression in Non-Immune Cells.

Interferon Regulatory Factor-8 (IRF-8) serves as a key factor in the hierarchical differentiation towards monocyte/dendritic cell lineages. While much insight has been accumulated into the mechanisms essential for its hematopoietic specific expression, the mode of restricting IRF-8 expression in non...

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Bibliographic Details
Main Authors: Mamduh Khateb, Nitsan Fourier, Ofer Barnea-Yizhar, Sigal Ram, Ekaterina Kovalev, Aviva Azriel, Ulfert Rand, Manabu Nakayama, Hansjörg Hauser, Lior Gepstein, Ben-Zion Levi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4892516?pdf=render

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http://europepmc.org/articles/PMC4892516?pdf=render

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