Synthesis of new enantiopure poly(hydroxy)aminooxepanes as building blocks for multivalent carbohydrate mimetics

Synthesis of new enantiopure poly(hydroxy)aminooxepanes as building blocks for multivalent carbohydrate mimetics

New compounds with carbohydrate-similar structure (carbohydrate mimetics) are presented in this article. Starting from enantiopure nitrones and lithiated TMSE-allene we prepared three 1,2-oxazine derivatives which underwent a highly stereoselective Lewis acid-induced rearrangement to give bicyclic p...

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Bibliographic Details
Main Authors: Léa Bouché, Maja Kandziora, Hans-Ulrich Reissig
Format: Article
Language:English
Published: Beilstein-Institut 2014-01-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
aminooxepanes
carbohydrate mimetics
hydrogenolyses
Lewis acid-induced
lithiated allenes
nitrones
1,2-oxazines
rearrangements
reductions
Online Access:https://doi.org/10.3762/bjoc.10.17

Internet

https://doi.org/10.3762/bjoc.10.17

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