Micro-computed tomography derived anisotropy detects tumor provoked deviations in bone in an orthotopic osteosarcoma murine model.

Radiographic imaging plays a crucial role in the diagnosis of osteosarcoma. Currently, computed-tomography (CT) is used to measure tumor-induced osteolysis as a marker for tumor growth by monitoring the bone fractional volume. As most tumors primarily induce osteolysis, lower bone fractional volume...

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Bibliographic Details
Main Authors: Heather A Cole, Tetsuro Ohba, Jiro Ichikawa, Jeffry S Nyman, Justin M M Cates, Hirotaka Haro, Herbert S Schwartz, Jonathan G Schoenecker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24892952/pdf/?tool=EBI