Mesenchymal Stem Cells Promote Pancreatic Tumor Growth by Inducing Alternative Polarization of Macrophages

Pancreatic cancer is characterized by an extensive desmoplastic stroma, the functional relevance of which is poorly understood. Activated fibroblasts are a prevalent component of the stroma, and traditionally, these cells have been considered as a homogenous population derived from pancreatic stella...

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Bibliographic Details
Main Authors: Esha Mathew, Arthur L. Brannon, AnnaChiara Del Vecchio, Paloma E. Garcia, Morgan K. Penny, Kevin T. Kane, Alekya Vinta, Ronald J. Buckanovich, Marina Pasca di Magliano
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558616000154