Pathway-based analysis using reduced gene subsets in genome-wide association studies

<p>Abstract</p> <p>Background</p> <p>Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to small marginal effects. Pathway level analysis incorporating prior...

Full description

Bibliographic Details
Main Authors: Liu Jianjun, Seielstad Mark, Gupta Simone, Zhao Jingyuan, Thalamuthu Anbupalam
Format: Article
Language:English
Published: BMC 2011-01-01
Series:BMC Bioinformatics
Online Access:http://www.biomedcentral.com/1471-2105/12/17