Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats

Sex-specific acute and chronic neurotoxicity of acute diisopropylfluorophosphate (DFP)-intoxication in juvenile Sprague-Dawley rats

Preclinical efforts to improve medical countermeasures against organophosphate (OP) chemical threat agents have largely focused on adult male models. However, age and sex have been shown to influence the neurotoxicity of repeated low-level OP exposure. Therefore, to determine the influence of sex an...

Full description

Bibliographic Details
Main Authors:	Eduardo A. González, Jonas J. Calsbeek, Yi-Hua Tsai, Mei-Yun Tang, Peter Andrew, Joan Vu, Elizabeth L. Berg, Naomi H. Saito, Danielle J. Harvey, Suangsuda Supasai, Gene G. Gurkoff, Jill L. Silverman, Pamela J. Lein
Format:	Article
Language:	English
Published:	Elsevier 2021-01-01
Series:	Current Research in Toxicology
Subjects:	Cognitive deficits Neurodegeneration Neurogenesis Neuroinflammation Seizures Sex differences
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666027X21000335

Similar Items

Aminoalcohol-Induced Activation of Organophosphorus Hydrolase (OPH) towards Diisopropylfluorophosphate (DFP).
by: Dandan Li, et al.
Published: (2017-01-01)

Author Correction: Organophosphorus diisopropylfluorophosphate (DFP) intoxication in zebrafish larvae causes behavioral defects, neuronal hyperexcitation and neuronal death
by: Alexandre Brenet, et al.
Published: (2021-03-01)

'Omic' Evaluation of the Region Specific Changes Induced by Non-Cholinergic Diisopropylfluorophosphate (DFP) Exposure in Fischer 344 Rat Brain
by: Mahle, Deirdre A.
Published: (2012)

Therapeutic Effect of Magnolol in Sprague-Dawley Rats Intoxicated with Acetaminophen
by: Yen-Yi Ho, et al.
Published: (2000)

Synthesis and Storage Stability of Diisopropylfluorophosphate
by: Derik R. Heiss, et al.
Published: (2016-01-01)

Serum Acetyl Cholinesterase as a Biomarker of Arsenic Induced Neurotoxicity in Sprague-Dawley Rats
by: Paul B. Tchounwou, et al.
Published: (2005-04-01)

Sub-Acute Toxicity Study of Graphene Oxide in the Sprague-Dawley Rat
by: Yingbo Li, et al.
Published: (2016-11-01)

Acute and Subchronic Oral Toxicity of Oil Palm Puree in Sprague–Dawley Rats
by: Zaida Zainal, et al.
Published: (2020-05-01)

ACUTE TOXICITY OF AQUOEUS EXTRACT OF Eupatorium riparium Reg. ON SPRAGUE-DAWLEY RATS
by: Nurlaila Nurlaila, et al.
Published: (2016-01-01)

The Effect of Callistephin on Amyloid Beta-Induced Neurotoxicity in the Hippocampus of Male Rats
by: Fahimeh Ghasemi Moravej, et al.
Published: (2017-07-01)

Acute oral toxicity of zein nanoparticles with encapsulated gamma oryzanol in Sprague Dawley rats
by: Rodsuwan Ubonphan, et al.
Published: (2021-01-01)

Acute and Subchronic Oral Toxicity Study of Gardenia Yellow E500 in Sprague-Dawley Rats
by: Xiaoqiao Tang, et al.
Published: (2020-01-01)

ACUTE ORAL TOXICITY STUDY OF AQUEOUS AND METHANOLIC EXTRACT OF BLUMEA VIRENS IN SPRAGUE DAWLEY RATS
by: Reni John, et al.
Published: (2017-12-01)

Acute Tocixity of Sterculia quadrifida R.Br Bark Ethanol Extract on Sprague-Dawley Rats
by: Siswadi Siswadi, et al.
Published: (2018-08-01)

Absence of toxicity of strobilanthes crispaJuice in acute oral toxicity study in sprague dawley rats
by: Norfarizan-Hanoon, N.A, et al.
Published: (2012)

Effects of Gelam and Acacia honey acute administration on some biochemical parameters of Sprague Dawley rats
by: Hussein, FN, et al.

Effects of Gelam and Acacia honey acute administration on some biochemical parameters of Sprague Dawley rats
by: Ismail, W.I.W, et al.
Published: (2014)

Complexity of the Electroencephalogram of the Sprague-Dawley Rat
by: Smith, Phillip James
Published: (2010)

Cyclophilin D Contributes to Anesthesia Neurotoxicity in the Developing Brain
by: Yiying Zhang, et al.
Published: (2020-02-01)

NEUROTOXIC EFFECTS OF AZT ON DEVELOPING AND ADULT NEUROGENESIS
by: Meryem eDemir, et al.
Published: (2015-03-01)

Neurotoxicity and neurobehavioral effects of manganese phosphate/sulfate mixture in male sprague-dawley rats following subchronic inhalation exposure
by: Salehi, Fariba
Published: (2017)

Evaluation of acute and subacute toxicity induced by methanol extract of Terminalia citrina leaves in Sprague Dawley rats
by: Narhari Das, et al.
Published: (2015-10-01)

ACUTE TOXICITY TEST OF ROSELLA (Hibiscus sabdariffa L.) CALYX ETHANOLIC EXTRACT ON Sprague Dawley RATS
by: Fita Sari, et al.
Published: (2016-04-01)

Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats.
by: Kristine Ljones, et al.
Published: (2017-01-01)

Inhibition of Perforin-Mediated Neurotoxicity Attenuates Neurological Deficits After Ischemic Stroke
by: Yuhualei Pan, et al.
Published: (2021-06-01)

Neuroinflammation as a Therapeutic Target for Mitigating the Long-Term Consequences of Acute Organophosphate Intoxication
by: Peter M. Andrew, et al.
Published: (2021-05-01)

Acute Isoniazid Neurotoxicity
by: J Gordon Millichap
Published: (1995-06-01)

Inducible nitric oxide synthase inhibitor, 1400W, mitigates DFP-induced long-term neurotoxicity in the rat model
by: Marson Putra, et al.
Published: (2020-01-01)

The metabolism of razoxane and dexrazoxane in the Sprague-Dawley rat
by: Aoyama, Ronald G.
Published: (2007)

The metabolism of razoxane and dexrazoxane in the Sprague-Dawley rat
by: Aoyama, Ronald G.
Published: (2007)

The metabolism of razoxane and dexrazoxane in the Sprague-Dawley rat
by: Aoyama, Ronald G.
Published: (2007)

Discriminant Analysis for Sprague-Dawley Rats with Sepsis
by: Chung-Lung Tsai, et al.
Published: (2008)

Correction: Acute exhaustive aerobic exercise training impair cardiomyocyte function and calcium handling in Sprague-Dawley rats.
by: PLOS ONE Staff
Published: (2018-01-01)

Acute toxicity evaluation of a crude sap isolated from Nypa fruticans Wurmb. in Sprague Dawley rats
by: Siti Fatimah Roqiah Yahaya, et al.
Published: (2021)

Urethane attenuates early neuropathology of diisopropylfluorophosphate-induced status epilepticus in rats
by: Asheebo Rojas, et al.
Published: (2020-07-01)

Ketamine-induced neurotoxicity in neurodevelopment: A synopsis of main pathways based on recent in vivo experimental findings
by: Konstantina Kalopita, et al.
Published: (2021-01-01)

Uterine torsion in a Sprague Dawley rat (Rattus norvegicus)
by: K. H. Erlwanger, et al.
Published: (2011-04-01)

Acute oral toxicity of pesticide combination (acephate 50% and imidacloprid 1.8% as active ingredients) in Sprague-Dawley rats
by: Rajendra Palkhade, et al.
Published: (2018-09-01)

Acute Wound Healing Potential of Marine Worm, Diopatra claparedii Grube, 1878 Aqueous Extract on Sprague Dawley Rats
by: Nor ‘Awatif Che Soh, et al.
Published: (2020-01-01)

Time-Course Responses of Muscle-Specific MicroRNAs Following Acute Uphill or Downhill Exercise in Sprague-Dawley Rats
by: Xin Yin, et al.
Published: (2019-10-01)