Effects of HLA-DRB1 alleles on susceptibility and clinical manifestations in Japanese patients with adult onset Still’s disease

Effects of HLA-DRB1 alleles on susceptibility and clinical manifestations in Japanese patients with adult onset Still’s disease

Abstract Background HLA-DRB1 alleles are major determinants of genetic predisposition to rheumatic diseases. We assessed whether DRB1 alleles are associated with susceptibility to particular clinical features of adult onset Still’s disease (AOSD) in a Japanese population by determining the DRB1 alle...

Full description

Bibliographic Details
Main Authors: Tomoyuki Asano, Hiroshi Furukawa, Shuzo Sato, Makiko Yashiro, Hiroko Kobayashi, Hiroshi Watanabe, Eiji Suzuki, Tomoyuki Ito, Yoshifumi Ubara, Daisuke Kobayashi, Nozomi Iwanaga, Yasumori Izumi, Keita Fujikawa, Satoshi Yamasaki, Tadashi Nakamura, Tomohiro Koga, Toshimasa Shimizu, Masataka Umeda, Fumiaki Nonaka, Michio Yasunami, Yukitaka Ueki, Katsumi Eguchi, Naoyuki Tsuchiya, Shigeto Tohma, Koh-ichiro Yoshiura, Hiromasa Ohira, Atsushi Kawakami, Kiyoshi Migita
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Arthritis Research & Therapy
Subjects:
Adult onset Still’s disease
Autoinflammatory disease
Human leukocyte antigen
Macrophage-activation syndrome
Systemic juvenile idiopathic arthritis
Online Access:http://link.springer.com/article/10.1186/s13075-017-1406-x

Internet

http://link.springer.com/article/10.1186/s13075-017-1406-x

Similar Items