Revealing Pathway Dynamics in Heart Diseases by Analyzing Multiple Differential Networks.

Development of heart diseases is driven by dynamic changes in both the activity and connectivity of gene pathways. Understanding these dynamic events is critical for understanding pathogenic mechanisms and development of effective treatment. Currently, there is a lack of computational methods that e...

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Bibliographic Details
Main Authors: Xiaoke Ma, Long Gao, Georgios Karamanlidis, Peng Gao, Chi Fung Lee, Lorena Garcia-Menendez, Rong Tian, Kai Tan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-06-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.1004332